Endocrine Abstracts

The Austrian Acromegaly Registry is an initiative of the Austrian Society for Endocrinology and Metabolism. This database includes 607 patients (54% females) followed in twelve centers. Mean treatment period is 10.7 years (range 0–50 years), the total number of patient-years is 6470. Here we report gender-specific differences in the presentation, therapy and biochemical control of acromegaly in patients included in this registry.Mean age at diagnosi...

Acromegaly is amongst other symptoms associated with myopathy, alterations of energy expenditure and insulin action which are mediated by growth hormone (GH) and insulin-like growth factors (IGFs). It is unclear to which extent these abnormalities remain after treatment. Thus, we examined glucose metabolism, intracellular fat deposition and mitochondrial function in patients with prior acromegaly (AM).Six AM (4f/2 m, age: 49±10 years, body mass inde...